Inhibition of spinal astrocytic c-Jun N-terminal kinase (JNK) activation correlates with the analgesic effects of ketamine in neuropathic pain

<p>Abstract</p> <p>Background</p> <p>We have previously reported that inhibition of astrocytic activation contributes to the analgesic effects of intrathecal ketamine on spinal nerve ligation (SNL)-induced neuropathic pain. However, the underlying mechanisms are still u...

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Bibliographic Details
Main Authors: Wang Wen, Zhai Ming-Zhu, Wei Yan-Yan, Wang Wei, Zhang Hui, Mei Xiao-Peng, Xu Li-Xian, Li Yun-Qing
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/6