Methyltransferase-directed orthogonal tagging and sequencing of miRNAs and bacterial small RNAs

Methyltransferase-directed orthogonal tagging and sequencing of miRNAs and bacterial small RNAs

Abstract Background Targeted installation of designer chemical moieties on biopolymers provides an orthogonal means for their visualisation, manipulation and sequence analysis. Although high-throughput RNA sequencing is a widely used method for transcriptome analysis, certain steps, such as 3′ adapt...

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Bibliographic Details
Main Authors: Milda Mickutė, Kotryna Kvederavičiūtė, Aleksandr Osipenko, Raminta Mineikaitė, Saulius Klimašauskas, Giedrius Vilkaitis
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Biology
Subjects:
Methyltransferase
RNA modification
RNA-seq
Non-coding RNA
Epitranscriptome
Probiotic
Online Access:https://doi.org/10.1186/s12915-021-01053-w

Internet

https://doi.org/10.1186/s12915-021-01053-w

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