Optimization of flask culture medium and conditions for hyaluronic acid production by a streptococcus equisimilis mutant nc2168

A mutant designated NC2168, which was selected from wild-type Streptococcus equisimilis CVCC55116by ultraviolet ray combined with60Co-γ ray treatment and does not produce streptolysin, was employed to produce hyaluronic acid (HA). In order to increase the output of HA in a flask, the cultur...

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Bibliographic Details
Main Authors: Yong-Hao Chen, Jun Li, Li Liu, Hong-Zhi Liu, Qiang Wang
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia 2012-12-01
Series:Brazilian Journal of Microbiology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000400040