Ovarian tumor attachment, invasion and vascularization reflect unique microenvironments in the peritoneum:Insights from xenograft and mathematical models

Ovarian tumor attachment, invasion and vascularization reflect unique microenvironments in the peritoneum:Insights from xenograft and mathematical models

Ovarian cancer relapse is often characterized by metastatic spread throughout the peritoneal cavity with tumors attached to multiple organs. In this study, interaction of ovarian tumor cells with the peritoneal tumor microenvironment was evaluated in a xenograft model based on intraperitoneal injec...

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Bibliographic Details
Main Authors: Mara P. Steinkamp, Kimberly eKanigel-Winner, Suzy eDavies, Carolyn Y. Muller, Yong eZhang, Robert M. Hoffman, Abbas eShirinifard, Melanie eMoses, Yi eJiang, Bridget S eWilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Oncology
Subjects:
Cell Adhesion
Tumor Microenvironment
metastasis
ovarian cancer
cellular Potts model
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00097/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00097/full

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