Adaptation to experimental jet-lag in R6/2 mice despite circadian dysrhythmia.

Adaptation to experimental jet-lag in R6/2 mice despite circadian dysrhythmia.

The R6/2 transgenic mouse model of Huntington's disease (HD) shows a disintegration of circadian rhythms that can be delayed by pharmacological and non-pharmacological means. Since the molecular machinery underlying the circadian clocks is intact, albeit progressively dysfunctional, we wondered...

Full description

Bibliographic Details
Main Authors: Nigel I Wood, Catherine J McAllister, Marc Cuesta, Juliet Aungier, Eloise Fraenkel, A Jennifer Morton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3563662?pdf=render

Internet

http://europepmc.org/articles/PMC3563662?pdf=render

Similar Items