Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells
<p>Abstract</p> <p>Background</p> <p>Obesity has been linked to an increased risk of female infertility. Leptin, an adipocytokine which is elevated during obesity, may influence gonadal function through modulating steroidogenesis in granulosa cells.</p> <p>M...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-10-01
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Series: | Reproductive Biology and Endocrinology |
Online Access: | http://www.rbej.com/content/7/1/115 |