Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells

<p>Abstract</p> <p>Background</p> <p>Obesity has been linked to an increased risk of female infertility. Leptin, an adipocytokine which is elevated during obesity, may influence gonadal function through modulating steroidogenesis in granulosa cells.</p> <p>M...

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Bibliographic Details
Main Authors: HoYuen Basil, Cheng Linan, Chen Junling, Poon Song, Lin Qing, Leung Peter CK
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/7/1/115