Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep
Abstract Background Sleep deprivation impairs learning, causes stress, and can lead to death. Notch and JNK-1 pathways impact C. elegans sleep in complex ways; these have been hypothesized to involve compensatory sleep. C. elegans DAF-16, a FoxO transcription factor, is required for homeostatic resp...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | BMC Neuroscience |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12868-018-0408-1 |