Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep

Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep

Abstract Background Sleep deprivation impairs learning, causes stress, and can lead to death. Notch and JNK-1 pathways impact C. elegans sleep in complex ways; these have been hypothesized to involve compensatory sleep. C. elegans DAF-16, a FoxO transcription factor, is required for homeostatic resp...

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Bibliographic Details
Main Authors: Heather L. Bennett, Yulia Khoruzhik, Dustin Hayden, Huiyan Huang, Jarred Sanders, Melissa B. Walsh, David Biron, Anne C. Hart
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Neuroscience
Subjects:
Compensatory sleep
daf-16
lag-2
Notch
Homeostasis
jnk-1
Online Access:http://link.springer.com/article/10.1186/s12868-018-0408-1

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