Aggressive chemotherapy and the selection of drug resistant pathogens.

Drug resistant pathogens are one of the key public health challenges of the 21st century. There is a widespread belief that resistance is best managed by using drugs to rapidly eliminate target pathogens from patients so as to minimize the probability that pathogens acquire resistance de novo. Yet s...

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Bibliographic Details
Main Authors: Silvie Huijben, Andrew S Bell, Derek G Sim, Danielle Tomasello, Nicole Mideo, Troy Day, Andrew F Read
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3771897?pdf=render