Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer
Abstract Background Colorectal cancer (CRC) is the second leading cancer killer in the US today and patients with metastatic disease have only a 14% 5-year survival. One of the most impactful recent advances in cancer therapy, immune checkpoint inhibition, has not been shown to be effective for the...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-020-6513-4 |