Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells

Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells

AIM: To explore the effect of parthenolide (PTL) on human uveal melanoma (UM) cells (C918 and SP6.5 cells) and its molecular mechanism. METHODS: Carboxyfluorescein succinimidyl amino ester (CFSE) assays and cell counting kit-8 (CCK-8) were performed to detect the cell viability. Flow cytometry was...

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Bibliographic Details
Main Authors: Song-Tian Che, Li Bie, Xu Li, Hui Qi, Peng Yu, Ling Zuo
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-10-01
Series:International Journal of Ophthalmology
Subjects:
parthenolide
uveal melanoma
proliferation
apoptosis
mitochondrial pathway
Online Access:http://www.ijo.cn/en_publish/2019/10/20191003.pdf

Internet

http://www.ijo.cn/en_publish/2019/10/20191003.pdf

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