A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.

Placental malaria caused by Plasmodium falciparum is a major cause of mortality and severe morbidity. Clinical testing of a soluble protein-based vaccine containing the parasite ligand, VAR2CSA, has been initiated. VAR2CSA binds to the human receptor chondroitin sulphate A (CSA) and is responsible f...

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Bibliographic Details
Main Authors: Susan Thrane, Christoph M Janitzek, Mette Ø Agerbæk, Sisse B Ditlev, Mafalda Resende, Morten A Nielsen, Thor G Theander, Ali Salanti, Adam F Sander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4657905?pdf=render

Internet

http://europepmc.org/articles/PMC4657905?pdf=render

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