Involvement of Nitric Oxide on Bothropoides insularis Venom Biological Effects on Murine Macrophages In Vitro.

Viperidae venom has several local and systemic effects, such as pain, edema, inflammation, kidney failure and coagulopathy. Additionally, bothropic venom and its isolated components directly interfere on cellular metabolism, causing alterations such as cell death and proliferation. Inflammatory cell...

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Bibliographic Details
Main Authors: Ramon R P P B de Menezes, Clarissa P Mello, Dânya B Lima, Louise D Tessarolo, Tiago Lima Sampaio, Lívia C F Paes, Natacha T Q Alves, Eudmar M Assis Junior, Roberto C P Lima Junior, Marcos H Toyama, Alice M C Martins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4790960?pdf=render