Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression

Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression

Hepatocellular carcinoma (HCC) is currently the third most common cause of cancer-related death in the Asia-Pacific region. Our previous work showed that knockdown of CD98 significantly inhibits malignant HCC cell phenotypes in vitro and in vivo. The level of CD98 in the membrane is tightly regulate...

Full description

Bibliographic Details
Main Authors: Bo Wu, Yang Zhou, Yu Wang, Xiang-Min Yang, Zhen-Yu Liu, Jiang-Hua Li, Fei Feng, Zhi-Nan Chen, Jian-Li Jiang
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:International Journal of Molecular Sciences
Subjects:
CD98 heavy chain
carcinoma
hepatocellular
disease progression
integrins
protein transport
Online Access:http://www.mdpi.com/1422-0067/17/11/1882

Internet

http://www.mdpi.com/1422-0067/17/11/1882

Similar Items