Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma

Background Temozolomide (TMZ) chemotherapy is a current standard of care for glioblastoma (GBM), however it has only extended overall survival by a few months. Because it also modulates the immune system, both beneficially and negatively, understanding how TMZ interacts with immunotherapeutics is im...

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Bibliographic Details
Main Authors: Dipongkor Saha, Samuel D Rabkin, Robert L Martuza
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000345.full