DNA Methylation in Inflammatory Pathways Modifies the Association between BMI and Adult-Onset Non-Atopic Asthma

DNA Methylation in Inflammatory Pathways Modifies the Association between BMI and Adult-Onset Non-Atopic Asthma

A high body mass (BMI) index has repeatedly been associated with non-atopic asthma, but the biological mechanism linking obesity to asthma is still poorly understood. We aimed to test the hypothesis that inflammation and/or innate immunity plays a role in the obesity-asthma link. DNA methylome was m...

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Bibliographic Details
Main Authors: Ayoung Jeong, Medea Imboden, Akram Ghantous, Alexei Novoloaca, Anne-Elie Carsin, Manolis Kogevinas, Christian Schindler, Gianfranco Lovison, Zdenko Herceg, Cyrille Cuenin, Roel Vermeulen, Deborah Jarvis, André F. S. Amaral, Florian Kronenberg, Paolo Vineis, Nicole Probst-Hensch
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Environmental Research and Public Health
Subjects:
adult-onset asthma
non-atopic asthma
obesity
inflammation
innate immunity
epigenetics
DNA methylation
epigenome-wide association study
Online Access:https://www.mdpi.com/1660-4601/16/4/600

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https://www.mdpi.com/1660-4601/16/4/600

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