MicroRNA-133a Inhibits Osteosarcoma Cells Proliferation and Invasion via Targeting IGF-1R

MicroRNA-133a Inhibits Osteosarcoma Cells Proliferation and Invasion via Targeting IGF-1R

Background/Aims: MicroRNAs (miRNAs) are a class of small noncoding RNAs that regulate gene expression by repressing translation or cleaving RNA transcripts in a sequence-specific manner. Downregulated microRNAs and their roles in cancer development have attracted much attention. A growing body of ev...

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Bibliographic Details
Main Authors: Guangnan Chen, Tingting Fang, Zhongming Huang, Yiying Qi, Shaohua Du, Tuoyu Di, Zhong Lei, Xiangyu Zhang, Weiqi Yan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Osteosarcoma
MicroRNA
MicroRNA-133a
IGF-1R
ERK/AKT signaling pathway
Online Access:http://www.karger.com/Article/FullText/438653

Internet

http://www.karger.com/Article/FullText/438653

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