The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism.

The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism.

The oxidative burst generated by the host immune system can restrict intracellular parasite entry and growth. While this burst leads to the induction of antioxidative enzymes, the molecular mechanisms and the consequences of this counter-response on the life of intracellular human parasites are larg...

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Bibliographic Details
Main Authors: Marta Reverte, Remzi Onur Eren, Baijayanti Jha, Chantal Desponds, Tiia Snäkä, Florence Prevel, Nathalie Isorce, Lon-Fye Lye, Katherine L Owens, Ulisses Gazos Lopes, Stephen M Beverley, Nicolas Fasel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009422

Internet

https://doi.org/10.1371/journal.ppat.1009422

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