Revealing the role of the human blood plasma proteome in obesity using genetic drivers

Blood circulating proteins reflect biological processes, thus providing insight into complex traits. Here the authors study the relationship between 1000 plasma proteins and body mass index (BMI), highlighting widespread proteome changes and causal relationships between BMI and specific proteins.

Bibliographic Details
Main Authors: Shaza B. Zaghlool, Sapna Sharma, Megan Molnar, Pamela R. Matías-García, Mohamed A. Elhadad, Melanie Waldenberger, Annette Peters, Wolfgang Rathmann, Johannes Graumann, Christian Gieger, Harald Grallert, Karsten Suhre
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21542-4