CD133-enriched Xeno-Free human embryonic-derived neural stem cells expand rapidly in culture and do not form teratomas in immunodeficient mice

Common methods for the generation of human embryonic-derived neural stem cells (hNSCs) result in cells with potentially compromised safety profiles due to maintenance of cells in conditions containing non-human proteins (e.g. in bovine serum or on mouse fibroblast feeders). Additionally, sufficient...

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Bibliographic Details
Main Authors: Daniel L. Haus, Hal X. Nguyen, Eric M. Gold, Noriko Kamei, Harvey Perez, Harry D. Moore, Aileen J. Anderson, Brian J. Cummings
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114000816