Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation

Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation

Hypertensive renal damage generally occurs during the middle and late stages of hypertension, which is typically characterized by proteinuria and renal inflammation. Captopril, an angiotensin-converting enzyme (ACE) inhibitor, has been widely used for therapy of arterial hypertension and cardiovascu...

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Bibliographic Details
Main Authors: Zhongyuan Gan, Dan Huang, Jiaye Jiang, Yuan Li, Hanqing Li, Yan Ke
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Captopril
Spontaneously hypertensive rats
Renal injury
Inflammation
Nuclear factor-κB
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001100602&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001100602&lng=en&tlng=en

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