UV-light effects on cytochrome c modulated by the aggregation state of phenothiazines.

The present study shows the factors that modulate the photodamage promoted by phenothiazines. Cytochrome c was irradiated with UV light for 120 min, over a pH range from 4.0 to 8.0, in the absence and in the presence of different concentrations of thioridazine (TR) and fluphenazine (FP). In the abse...

Full description

Bibliographic Details
Main Authors: Carolina G dos Santos, André L Silva, Flavio L Souza, Alexandre J C Lanfredi, Paolo Di Mascio, Otaciro R Nascimento, Tiago Rodrigues, Iseli L Nantes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3793907?pdf=render