The Tumor Suppressor <i>PTEN</i> as Molecular Switch Node Regulating Cell Metabolism and Autophagy: Implications in Immune System and Tumor Microenvironment

The Tumor Suppressor <i>PTEN</i> as Molecular Switch Node Regulating Cell Metabolism and Autophagy: Implications in Immune System and Tumor Microenvironment

Recent studies conducted over the past 10 years evidence the intriguing role of the tumor suppressor gene Phosphatase and Tensin Homolog deleted on Chromosome 10 <i>PTEN</i> in the regulation of cellular energy expenditure, together with its capability to modulate proliferation and survi...

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Bibliographic Details
Main Authors: Saveria Aquila, Marta Santoro, Annalisa Caputo, Maria Luisa Panno, Vincenzo Pezzi, Francesca De Amicis
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
Warburg state
cancer metabolism
stroma
immune system
Online Access:https://www.mdpi.com/2073-4409/9/7/1725

Internet

https://www.mdpi.com/2073-4409/9/7/1725

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