Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes

Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes

Abstract Background High-grade endometrioid and serous endometrial cancers (ECs) are an aggressive subtype of ECs without effective therapies. The reciprocal communication between tumor cells and their surrounding microenvironment drives tumor progression. Long noncoding RNAs (lncRNAs) are key media...

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Bibliographic Details
Main Authors: Peixin Dong, Ying Xiong, Junming Yue, Daozhi Xu, Kei Ihira, Yosuke Konno, Noriko Kobayashi, Yukiharu Todo, Hidemichi Watari
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
NEAT1
miR-361
STAT3
Endometrial cancer metastasis
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s13046-019-1306-9

Internet

http://link.springer.com/article/10.1186/s13046-019-1306-9

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