Synthesis of Trichodermin Derivatives and Their Antimicrobial and Cytotoxic Activities

Synthesis of Trichodermin Derivatives and Their Antimicrobial and Cytotoxic Activities

Trichothecene mycotoxins are recognized as highly bioactive compounds that can be used in the design of new useful bioactive molecules. In <i>Trichoderma brevicompactum</i>, the first specific step in trichothecene biosynthesis is carried out by a terpene cyclase, trichodiene synthase, t...

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Bibliographic Details
Main Authors: Javier E. Barúa, Mercedes de la Cruz, Nuria de Pedro, Bastien Cautain, Rosa Hermosa, Rosa E. Cardoza, Santiago Gutiérrez, Enrique Monte, Francisca Vicente, Isidro G. Collado
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
trichothecene
sesquiterpenes
<i>tri</i> genes
synthesis
antimicrobial
cytotoxic bioactivity
Online Access:https://www.mdpi.com/1420-3049/24/20/3811

Internet

https://www.mdpi.com/1420-3049/24/20/3811

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