PACAP Neurons in the Ventromedial Hypothalamic Nucleus Are Glucose Inhibited and Their Selective Activation Induces Hyperglycaemia

Background: Glucose-sensing neurons are located in several parts of the brain, but are concentrated in the ventromedial nucleus of the hypothalamus (VMH). The importance of these VMH neurons in glucose homeostasis is well-established, however, little is known about their individual identity. In the...

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Bibliographic Details
Main Authors: Tansi Khodai, Nicolas Nunn, Amy A. Worth, Claire H. Feetham, Mino D. C. Belle, Hugh D. Piggins, Simon M. Luckman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Endocrinology
Subjects:
VMH
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00632/full