Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.

Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.

A substantial proportion of familial colorectal cancer (CRC) is not a consequence of known susceptibility loci, such as mismatch repair (MMR) genes, supporting the existence of additional loci. To identify novel CRC loci, we conducted a genome-wide linkage scan in 356 white families with no evidence...

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Bibliographic Details
Main Authors: Mine S Cicek, Julie M Cunningham, Brooke L Fridley, Daniel J Serie, William R Bamlet, Brenda Diergaarde, Robert W Haile, Loic Le Marchand, Theodore G Krontiris, H Banfield Younghusband, Steven Gallinger, Polly A Newcomb, John L Hopper, Mark A Jenkins, Graham Casey, Fredrick Schumacher, Zhu Chen, Melissa S DeRycke, Allyson S Templeton, Ingrid Winship, Roger C Green, Jane S Green, Finlay A Macrae, Susan Parry, Graeme P Young, Joanne P Young, Daniel Buchanan, Duncan C Thomas, D Timothy Bishop, Noralane M Lindor, Stephen N Thibodeau, John D Potter, Ellen L Goode, Colon CFR
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364975?pdf=render

Internet

http://europepmc.org/articles/PMC3364975?pdf=render

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