Structural basis of the complementary activity of two ketosynthases in aryl polyene biosynthesis

Abstract Aryl polyenes (APE) are one of the most widespread secondary metabolites among gram-negative bacteria. In Acinetobacter baumannii, strains belonging to the virulent global clone 2 (GC2) mostly contain APE biosynthesis genes; its relevance in elevated pathogenicity is of great interest. APE...

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Bibliographic Details
Main Authors: Woo Cheol Lee, Sungjae Choi, Ahjin Jang, Jiwon Yeon, Eunha Hwang, Yangmee Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95890-y