Bone Fracture Enhanced Blood-Brain Barrier Breakdown in the Hippocampus and White Matter Damage of Stroke Mice

Bone Fracture Enhanced Blood-Brain Barrier Breakdown in the Hippocampus and White Matter Damage of Stroke Mice

Background: Tibia fracture (BF) before stroke shortly causes long-term post-stroke memory dysfunction in mice. The mechanism is unclear. We hypothesize that BF enhances neuroinflammation and blood brain barrier (BBB) breakdown in the hippocampus and white matter (WM) damage. Methods: Mice were assig...

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Bibliographic Details
Main Authors: Jinhao Huang, Haiyan Lyu, Kang Huo, Leandro B. Do Prado, Chaoliang Tang, Zhanqiang Wang, Qifeng Li, Julia Wong, Hua Su
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
stroke
bone fracture
blood brain barrier breakdown
white matter damage
hippocampus
Online Access:https://www.mdpi.com/1422-0067/21/22/8481

Internet

https://www.mdpi.com/1422-0067/21/22/8481

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