Genetic engineering of human NK cells to express CXCR2 improves migration to renal cell carcinoma

Genetic engineering of human NK cells to express CXCR2 improves migration to renal cell carcinoma

Abstract Background Adoptive natural killer (NK) cell transfer is being increasingly used as cancer treatment. However, clinical responses have so far been limited to patients with hematological malignancies. A potential limiting factor in patients with solid tumors is defective homing of the infuse...

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Bibliographic Details
Main Authors: Veronika Kremer, Marteen A. Ligtenberg, Rosa Zendehdel, Christina Seitz, Annet Duivenvoorden, Erik Wennerberg, Eugenia Colón, Ann-Helén Scherman-Plogell, Andreas Lundqvist
Format: Article
Language:English
Published: BMJ Publishing Group 2017-09-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
NK cells
Chemokines
CXCR2
Renal cell carcinoma
Adoptive cell therapy
Online Access:http://link.springer.com/article/10.1186/s40425-017-0275-9

Internet

http://link.springer.com/article/10.1186/s40425-017-0275-9

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