Decoding Neuromuscular Disorders Using Phenotypic Clusters Obtained From Co-Occurrence Networks

Decoding Neuromuscular Disorders Using Phenotypic Clusters Obtained From Co-Occurrence Networks

Neuromuscular disorders (NMDs) represent an important subset of rare diseases associated with elevated morbidity and mortality whose diagnosis can take years. Here we present a novel approach using systems biology to produce functionally-coherent phenotype clusters that provide insight into the cell...

Full description

Bibliographic Details
Main Authors: Elena Díaz-Santiago, M. Gonzalo Claros, Raquel Yahyaoui, Yolanda de Diego-Otero, Rocío Calvo, Janet Hoenicka, Francesc Palau, Juan A. G. Ranea, James R. Perkins
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
neuromuscular disorders
rare disease
phenotype
network analysis
cluster
co-occurrence analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.635074/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.635074/full

Similar Items