A hepatitis C virus infection model with time-varying drug effectiveness: solution and analysis.
Simple models of therapy for viral diseases such as hepatitis C virus (HCV) or human immunodeficiency virus assume that, once therapy is started, the drug has a constant effectiveness. More realistic models have assumed either that the drug effectiveness depends on the drug concentration or that the...
Main Authors: | Jessica M Conway, Alan S Perelson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-08-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4125050?pdf=render |
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