Functional Characterization of Entamoeba histolytica Argonaute Proteins Reveals a Repetitive DR-Rich Motif Region That Controls Nuclear Localization

Functional Characterization of Entamoeba histolytica Argonaute Proteins Reveals a Repetitive DR-Rich Motif Region That Controls Nuclear Localization

The protozoan parasite Entamoeba histolytica, which causes amebiasis and affects over 50 million people worldwide, contains an important RNAi pathway for gene silencing. Gene silencing via the RNAi pathway is mediated by the Argonaute (Ago) proteins. However, we lack knowledge on Ago function(s) in...

Full description

Bibliographic Details
Main Authors: Hanbang Zhang, Vy Tran, Dipak Manna, Gretchen Ehrenkaufer, Upinder Singh
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mSphere
Subjects:
argonaute proteins
entamoeba
rna interference
gene expression
transcriptional regulation
Online Access:https://doi.org/10.1128/mSphere.00580-19

Internet

https://doi.org/10.1128/mSphere.00580-19

Similar Items