Lack of intrafollicular memory CD4 + T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma

Abstract Despite a characteristic indolent course, a substantial subset of follicular lymphoma (FL) patients has an early relapse with a poor outcome. Cells in the microenvironment may be a key contributor to treatment failure. We used a discovery and validation study design to identify microenviron...

Full description

Bibliographic Details
Main Authors: Patrizia Mondello, Angelo Fama, Melissa C. Larson, Andrew L. Feldman, Jose C. Villasboas, Zhi-Zhang Yang, Ilia Galkin, Viktor Svelolkin, Ekaterina Postovalova, Alexander Bagaev, Pavel Ovcharov, Arina Varlamova, Sarah Huet, Bruno Tesson, Kaitlyn R. McGrath, Susan Slager, Brian K. Link, Sergei Syrbu, Anne J. Novak, Thomas M. Habermann, Thomas E. Witzig, Grzegorz S. Nowakowski, Gilles Salles, James R. Cerhan, Stephen M. Ansell
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-021-00521-4