Detection of somatic mutations by high-resolution DNA melting (HRM) analysis in multiple cancers.

Detection of somatic mutations by high-resolution DNA melting (HRM) analysis in multiple cancers.

Identification of somatic mutations in cancer is a major goal for understanding and monitoring the events related to cancer initiation and progression. High resolution melting (HRM) curve analysis represents a fast, post-PCR high-throughput method for scanning somatic sequence alterations in target...

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Bibliographic Details
Main Authors: Jesus Gonzalez-Bosquet, Jacob Calcei, Jun S Wei, Montserrat Garcia-Closas, Mark E Sherman, Stephen Hewitt, Joseph Vockley, Jolanta Lissowska, Hannah P Yang, Javed Khan, Stephen Chanock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3022009?pdf=render

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http://europepmc.org/articles/PMC3022009?pdf=render

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