Quantitative Analysis of Somatostatin and Dopamine Receptors Gene Expression Levels in Non-functioning Pituitary Tumors and Association with Clinical and Molecular Aggressiveness Features

Quantitative Analysis of Somatostatin and Dopamine Receptors Gene Expression Levels in Non-functioning Pituitary Tumors and Association with Clinical and Molecular Aggressiveness Features

The primary treatment for non-functioning pituitary tumors (NFPTs) is surgery, but it is often unsuccessful. Previous studies have reported that NFPTs express receptors for somatostatin (SST<sub>1-5</sub>) and dopamine (DRDs) providing a rationale for the use of dopamine agonists and som...

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Bibliographic Details
Main Authors: Álvaro Flores-Martinez, Eva Venegas-Moreno, Elena Dios, Pablo Remón-Ruiz, Noelia Gros-Herguido, M. Carmen Vázquez-Borrego, Ainara Madrazo-Atutxa, Miguel A. Japón, Ariel Kaen, Eugenio Cárdenas-Valdepeñas, Florinda Roldán, Justo P. Castaño, Raúl M. Luque, David A. Cano, Alfonso Soto-Moreno
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Journal of Clinical Medicine
Subjects:
pituitary tumor
invasion
somatostatin receptor
dopamine receptor
non-functioning pituitary tumors
Online Access:https://www.mdpi.com/2077-0383/9/9/3052

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https://www.mdpi.com/2077-0383/9/9/3052

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