Determination by Site-directed Mutagenesis of Sites in Sepiapterin Reductase Phosphorylated by Ca2+/Calmodulin-dependent Protein Kinase II

Phosphorylation sites of sepiapterin reductase (SPR) phosphorylated by Ca2+-dependent protein kinase II (CaM KII) were studied. By immunoreaction against phosphorylated amino acids, we found that Ser residues of SPR were phosphorylated. We constructed several point mutants of SPR by site-directed mu...

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Bibliographic Details
Main Authors: Fujimoto Kengo, Inaba Akemi, Tomomura Akito, Katoh Setsuko
Format: Article
Language:English
Published: De Gruyter 2000-08-01
Series:Pteridines
Subjects:
Online Access:https://doi.org/10.1515/pteridines.2000.11.3.81