The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease

Abstract Non-alcoholic fatty liver disease (NAFLD) affects over 30% of adults in the United States. Bone morphogenetic protein (BMP) signaling is known to contribute to hepatic fibrosis, but the role of BMP signaling in the development of NAFLD is unclear. In this study, treatment with either of two...

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Bibliographic Details
Main Authors: Timothy E. Thayer, Christian L. Lino Cardenas, Trejeeve Martyn, Christopher J. Nicholson, Lisa Traeger, Florian Wunderer, Charles Slocum, Haakon Sigurslid, Hannah R. Shakartzi, Caitlin O’Rourke, Georgia Shelton, Mary D. Buswell, Hanna Barnes, Leif R. Neitzel, Clara D. Ledsky, Jason Pingcheng Li, Megan F. Burke, Eric Farber-Eger, Daniel S. Perrien, Ravindra Kumar, Kathleen E. Corey, Quinn S. Wells, Kenneth D. Bloch, Charles C. Hong, Donald B. Bloch, Rajeev Malhotra
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-66770-8