A genetic risk score combining ten psoriasis risk loci improves disease prediction.

A genetic risk score combining ten psoriasis risk loci improves disease prediction.

Psoriasis is a chronic, immune-mediated skin disease affecting 2-3% of Caucasians. Recent genetic association studies have identified multiple psoriasis risk loci; however, most of these loci contribute only modestly to disease risk. In this study, we investigated whether a genetic risk score (GRS)...

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Bibliographic Details
Main Authors: Haoyan Chen, Annie Poon, Celestine Yeung, Cynthia Helms, Jennifer Pons, Anne M Bowcock, Pui-Yan Kwok, Wilson Liao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084857?pdf=render

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http://europepmc.org/articles/PMC3084857?pdf=render

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