Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis

Abstract Background The role of miR-23b-3p in insulin resistance (IR) remained poorly understood. Methods After acacetin injection, obesity-induced IR model was constructed with or without miR-23b-3p upregulation and Neuraminidase 1 (NEU1) overexpression in mice. Body weight, serum metabolite and fa...

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Bibliographic Details
Main Authors: Yan Wei, Jianhong Jing, Zhiping Peng, Xiaoqian Liu, Xueyang Wang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Endocrine Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12902-021-00688-8