Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis
Abstract Background The role of miR-23b-3p in insulin resistance (IR) remained poorly understood. Methods After acacetin injection, obesity-induced IR model was constructed with or without miR-23b-3p upregulation and Neuraminidase 1 (NEU1) overexpression in mice. Body weight, serum metabolite and fa...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | BMC Endocrine Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12902-021-00688-8 |