Fragile X syndrome and fragile X-associated disorders [version 1; referees: 2 approved]
Fragile X syndrome (FXS) is caused by a full mutation on the FMR1 gene and a subsequent lack of FMRP, the protein product of FMR1. FMRP plays a key role in regulating the translation of many proteins involved in maintaining neuronal synaptic connections; its deficiency may result in a range of intel...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2017-12-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | https://f1000research.com/articles/6-2112/v1 |