Degradation Rate of 5-Fluorouracil in Metastatic Colorectal Cancer: A New Predictive Outcome Biomarker?

Degradation Rate of 5-Fluorouracil in Metastatic Colorectal Cancer: A New Predictive Outcome Biomarker?

BACKGROUND:5-FU based chemotherapy is the most common first line regimen used for metastatic colorectal cancer (mCRC). Identification of predictive markers of response to chemotherapy is a challenging approach for drug selection. The present study analyzes the predictive role of 5-FU degradation rat...

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Bibliographic Details
Main Authors: Andrea Botticelli, Marina Borro, Concetta Elisa Onesti, Lidia Strigari, Giovanna Gentile, Bruna Cerbelli, Adriana Romiti, Mario Occhipinti, Claudia Sebastiani, Luana Lionetto, Luca Marchetti, Maurizio Simmaco, Paolo Marchetti, Federica Mazzuca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5033390?pdf=render

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http://europepmc.org/articles/PMC5033390?pdf=render

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