Exome Sequencing Identifies TENM4 as a Novel Candidate Gene for Schizophrenia in the SCZD2 Locus at 11q14-21

Exome Sequencing Identifies TENM4 as a Novel Candidate Gene for Schizophrenia in the SCZD2 Locus at 11q14-21

Schizophrenia is a complex psychiatric disorder with high genetic heterogeneity, however, the contribution of rare mutations to the disease etiology remains to be further elucidated. We herein performed exome sequencing in a Han Chinese schizophrenia family and identified a missense mutation (c.6724...

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Bibliographic Details
Main Authors: Chao-Biao Xue, Zhou-Heng Xu, Jun Zhu, Yu Wu, Xi-Hang Zhuang, Qu-Liang Chen, Cai-Ru Wu, Jin-Tao Hu, Hou-Shi Zhou, Wei-Hang Xie, Xin Yi, Shan-Shan Yu, Zhi-Yu Peng, Huan-Ming Yang, Xiao-Hong Hong, Jian-Huan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Genetics
Subjects:
association
co-segregation
schizophrenia
exome analysis
rare mutation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00725/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00725/full

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