GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells

GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells

Gap junction protein, alpha 1 (GJA1), which is correlated with recurrences and unfavorable prognoses in hepatocellular carcinomas (HCCs), is one of the specific proteins expressed by activated hepatic stellate cells (HSCs).

Bibliographic Details
Main Authors: Niu Gengming, Zhang Xiaotian, Hong Runqi, Yang Ximin, Gu Jiawei, Song Tao, Hu Zhiqing, Chen Liang, Wang Xin, Xia Jie, Ke Zhongwei, Ren Jun, Hong Liang
Format: Article
Language:English
Published: De Gruyter 2021-09-01
Series:Open Medicine
Subjects:
hepatocellular carcinoma
metastasis
hepatic stellate cell
tgf-β
epithelial–mesenchymal transition
Online Access:https://doi.org/10.1515/med-2021-0344

Internet

https://doi.org/10.1515/med-2021-0344

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