A nadA Mutation Confers Nicotinic Acid Auxotrophy in Pro-carcinogenic Intestinal Escherichia coli NC101

A nadA Mutation Confers Nicotinic Acid Auxotrophy in Pro-carcinogenic Intestinal Escherichia coli NC101

Inflammatory bowel diseases (IBDs) and inflammation-associated colorectal cancer (CRC) are linked to blooms of adherent-invasive Escherichia coli (AIEC) in the intestinal microbiota. AIEC are functionally defined by their ability to adhere/invade epithelial cells and survive/replicate within macroph...

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Bibliographic Details
Main Authors: Lacey R. Lopez, Cassandra J. Barlogio, Christopher A. Broberg, Jeremy Wang, Janelle C. Arthur
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
inflammatory bowel disease
adherent invasive E. coli
Escherichia coli
auxotrophy
nicotinic acid
E. coli NC101
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.670005/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.670005/full

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