Determination of D816V mutation in the c-kIt gene in the Slovenian patients with acute myeloid leukemia and systemic mastocytosis

Background: D816V mutation in the C-KIT gene is present in more than 90 % of patients with systemic mastocytosis (SM) and 2–7 % of patients with acute myeloid leukemia (AML). D816V mutation is caused by the substitution of adenine with thymine at 2447 nucleotide sequence in the C-KIT gene. This...

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Bibliographic Details
Main Authors: Martina Fink, Peter Černelč, Tadej Pajič
Format: Article
Language:English
Published: Slovenian Medical Association 2012-12-01
Series:Zdravniški Vestnik
Online Access:http://vestnik.szd.si/index.php/ZdravVest/article/view/754