Determination of D816V mutation in the c-kIt gene in the Slovenian patients with acute myeloid leukemia and systemic mastocytosis
Background: D816V mutation in the C-KIT gene is present in more than 90 % of patients with systemic mastocytosis (SM) and 2–7 % of patients with acute myeloid leukemia (AML). D816V mutation is caused by the substitution of adenine with thymine at 2447 nucleotide sequence in the C-KIT gene. This...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Slovenian Medical Association
2012-12-01
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Series: | Zdravniški Vestnik |
Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/754 |