Discovery of RSV-Induced BRD4 Protein Interactions Using Native Immunoprecipitation and Parallel Accumulation—Serial Fragmentation (PASEF) Mass Spectrometry

Respiratory Syncytial Virus (RSV) causes severe inflammation and airway pathology in children and the elderly by infecting the epithelial cells of the upper and lower respiratory tract. RSV replication is sensed by intracellular pattern recognition receptors upstream of the IRF and NF-κB transcripti...

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Bibliographic Details
Main Authors: Morgan Mann, David S. Roberts, Yanlong Zhu, Yi Li, Jia Zhou, Ying Ge, Allan R. Brasier
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
RSV
PPI
AP1
Wnt
Online Access:https://www.mdpi.com/1999-4915/13/3/454