Evaluation of the paraoxonase-1 kinetic parameters of the lactonase activity by nonlinear fit of progress curves

Although paraoxonase-1 (PON1) activity has been demonstrated to be a reliable biomarker of various diseases, clinical studies have been based only on relative comparison of specific enzyme activities, which capture differences mainly due to (usually unknown) PON1 concentration. Hence, the aim of thi...

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Bibliographic Details
Main Authors: Marko Goličnik, Aljoša Bavec
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:http://dx.doi.org/10.1080/14756366.2019.1695792