HMGB1, S100 proteins and other RAGE ligands in cancer - markers, mediators and putative therapeutic targets

Background and Aims: Activation of RAGE due to its increased expression in cancer cells or its stimulation by multiple ligands (AGEs, HMGB1, S100 proteins, etc.) may contribute to the proliferation, invasiveness of tumor cells and formation of distant metastases and also to the resistance of cancer...

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Bibliographic Details
Main Authors: Petra Tesarova, Marta Kalousova, Tomas Zima, Vladimir Tesar
Format: Article
Language:English
Published: Palacký University Olomouc, Faculty of Medicine and Dentistry 2016-03-01
Series:Biomedical Papers
Subjects:
Online Access:https://biomed.papers.upol.cz/artkey/bio-201601-0001_HMGB1_S100_proteins_and_other_RAGE_ligands_in_cancer_-_markers_mediators_and_putative_therapeutic_targets.php