Efficient purification of cell culture-derived classical swine fever virus by ultrafiltration and size-exclusion chromatography
Large-scale production of cell culture-based classical swine fever virus (CSFV) vaccine is hampered by the adverse reactions caused by contaminants from host cell and culture medium. Hence, we have developed an efficient method for purifying CSFV from cell-culture medium. Pure viral particles were o...
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Format: | Article |
Language: | English |
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Higher Education Press
2015-09-01
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Series: | Frontiers of Agricultural Science and Engineering |
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Online Access: | http://academic.hep.com.cn/fase/fileup/2095-7505/PDF/2095-7505-2015-3-230.pdf |